CAS NO:868074-65-1 Aminolevulinic Acid Phosphate

CAS NO:868074-65-1 Aminolevulinic Acid Phosphate

Molecular Formula:C5H12NO7P
Molecular weight:229.12
Application:Used as a photosensitizer precursor, the core is applied in the fields of photodynamic diagnosis and treatment (PDD/PDT) industry.
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Description
Technical Parameters

 

Products Description

 

 

5-Aminolevulinic acid phosphate is the stable phosphate salt form of 5-ALA. It features low hygroscopicity and much better solid stability compared with hydrochloride salt. It has excellent water solubility and releases 5-ALA in aqueous solution to participate in porphyrin biosynthesis.

With low impurities and fewer side reactions, it brings little background interference in photodynamic experiments. It can be applied in multiple scenarios including biomedical research, agricultural enhancement and cosmetic antioxidation, with a wider applicable pH range and easier storage.

 

Products  Specification

 

Product name Aminolevulinic acid phosphate
CAS NO 868074-65-1
ITEM NO M861
Appearance White to off-white crystalline powder
Purity ≥99%
pH 2.5 ~ 3.5
Drying loss ≤1.0%
Heavy metals(as Pb) ≤10 ppm
Package 100mg/1g/100g etc.
Delivery 2-3days
Storage 2-8℃
MSDS/COA/TDS Connect us

 

Products Application

 

 

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1. Pharmaceutical intermediates: 5-ALA phosphate is an important intermediate in the pharmaceutical field, participating in the synthesis process of various drugs.
2. Organic reagents: In chemical research, it is often used as an organic reagent for various chemical reactions and synthesis processes.
3. Medical applications: Due to its ability to accumulate in cancer cells and emit light under specific light irradiation, 5-ALA phosphate is used in the medical field to identify cancer sites during surgeries.
4. Biological functions: 5-ALA phosphate is the raw material for heme, supporting the production of heme, which is crucial for the operation of mitochondria.

FAQ

 

Q: How to store Aminolevulinic acid phosphate?

A: Seal and protect from light, store at 2-8℃ under dry condition. Avoid high temperature and light to prevent degradation.

Q: What is its principle in photodynamic experiments?

A: It converts into Protoporphyrin IX inside cells. Under specific wavelength light irradiation, it generates reactive oxygen species to damage actively proliferating cells for photodynamic research.

Q: Could it be directly used for human clinic?

A: This product is for research only, not for direct human use. Clinical preparations must comply with pharmaceutical GMP standards.

Q: Is 5-Aminolevulinic acid phosphate prone to moisture absorption?

A: Compared with 5-ALA hydrochloride, this product has lower hygroscopicity. The solid powder is not easy to absorb moisture and agglomerate, making storage and operation simpler.

 

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