CAS NO:70024-51-0/55844-94-5 MERRIFIELD RESIN

CAS NO:70024-51-0/55844-94-5 MERRIFIELD RESIN
Merrifield Resin is one of the preferred materials for peptide synthesis, combinatorial chemistry, or when you need an insoluble polymeric carrier to simplify separation and purification steps.

Key characteristics:
Insoluble: Due to its high degree of cross-linking, it is insoluble in common solvents (such as water, alcohol, ether, benzene, etc.), but it will swell in these solvents.

Cross-linking degree (DVB%): cross-linked by divinylbenzene (DVB), 1% or 2% specifications are common. The degree of cross-linking affects its mechanical strength and swelling behavior.
 

1. Solid-phase peptide synthesis (SPPS) and solid-phase organic synthesis (SPOS)
In biochemistry fields such as peptide synthesis and oligonucleotide synthesis, it serves as a solid-phase synthesis carrier, enabling stepwise molecular linking and purification through the reaction of chloromethyl groups with functional groups such as the amino groups of amino acids or nucleotides;

2. Polymer reagents and catalysts;

3. Polymer carriers and separation;

4. Precursors of ion exchange resins;

5. Functional material modification: As a cross-linking agent or modified monomer, it is used to improve the properties of polymer materials, such as improving heat resistance, mechanical strength, etc. It has potential applications in electronic packaging, coatings, adhesives, and other fields.
 

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