Products Description
AKG(CAS NO:328-50-7) is a key intermediate in the tricarboxylic acid cycle (TCA cycle) and is itself an organic acid. Based on this core molecule, through salting out or combining with amino acids, an entire product family has been derived. Different forms have distinct characteristics in terms of solubility, pH, taste, and compatibility, which directly determine whether it is suitable for making tablets, beverages, or powder-based oral liquids.
AKG(CAS NO:328-50-7) is a naturally occurring core metabolic intermediate substance in the human tricarboxylic acid cycle. It is involved in key physiological processes such as human energy metabolism, amino acid synthesis, and ammonia detoxification. It is an endogenous active substance contained within the human body and is not an emerging synthetic concept raw material.
Products Specification
| Product name | AKG/2-Ketoglutaric acid |
| CAS NO | 328-50-7 |
| ITEM NO | M357 |
| Appearance | White crystalline powder |
| Purity | ≥99% |
| Residue on Ignition | ≤0.5% |
| Loss on Drying | ≤0.5% |
| Melting point | 114℃~116℃ |
| Package | 100mg/1g/1kg etc. |
| Delivery | 5-8days |
| Storage | room temperature |
| MSDS/COA/TDS | Connect us |
Products Application
AKG(CAS 328-50-7) series materials are widely used in dietary supplements, sports nutrition, clinical special food, biomedicine and cell culture research. Ca-AKG is for anti-aging formulas, AAKG for fitness supplements, free AKG and Mg-AKG for lab research and premium custom nutrition.

Megma also offers the AKG basic mineral salt series, including free α‑ketoglutaric acid, Ca‑AKG, Mg‑AKG, Na‑AKG and K‑AKG:
Free AKG features good water solubility and strong acidity, mostly used for research and synthesis scenarios requiring AKG in acid form;
Ca‑AKG is the mainstream variant with near‑neutral pH and excellent stability. It is available in four grades: granule, powder, superfine powder and water-soluble type, suitable for tablets, capsules and various solid formulations;
Mg‑AKG is the magnesium salt, ideal for sports nutrition and mineral supplement formulas with magnesium fortification;
Na‑AKG has outstanding water solubility, suitable for liquid formulations such as oral liquids and beverages where sodium content is not a concern;
K‑AKG is the potassium salt formulated for low‑sodium applications, widely used in isotonic drinks and sports electrolyte powders.
FAQ
Q1:How to select among different AKG mineral salts?
Re: For solid tablet capsules, Ca-AKG is preferred; for magnesium supplementation during exercise, Mg-AKG is selected; for making oral liquid beverages, Na-AKG can be chosen; if sodium control and potassium supplementation are needed, K-AKG should be selected; for scientific research synthesis, free AKG is used.
Q2:What is the difference between Na-AKG and K-AKG for liquid beverage formulas?
Re:Na-AKG has a high solubility, making it suitable for beverages without sodium restrictions; K-AKG focuses on low-sodium formulations, suitable for electrolyte and isotonic sports drinks.
Q3:How is AKG stored?
Re: Store in a sealed container in a cool, dry and well-ventilated place, away from strong light and heat sources. Use up quickly after opening to prevent moisture absorption.
Q4: Could it be added directly into drinks?
Re: Yes, pH control is recommended, buffer system is needed for some formulas.
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