CAS NO:26124-68-5 PGA/POLYGLYCOLIDE

CAS NO:26124-68-5 PGA/POLYGLYCOLIDE

Molecular Formula:C2H4O3
Molecular weight:76.05
Application:Used in the field of biomedicine, it is used to produce fast-absorbing surgical sutures, orthopedic implant fixation devices, tissue engineering scaffolds and wound repair materials.
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Description
Technical Parameters

 

Products Description

 

PGA(CAS  26124-68-5)is a type of linear polyester polymer with the lowest carbon number, a completely degradable ester structure, and the fastest degradation rate. It is a fatty acid-based polymer with excellent biocompatibility, biodegradability, and mechanical strength.
PGA has a regular molecular structure and tightly packed chain segments, making it a highly crystalline thermoplastic polymer. Its crystallinity is typically around 55%. The melting point (Tm) of PGA is very high, ranging from 220 to 230 °C, which is approximately 50 °C higher than PLA and P3HB [6]. The glass transition temperature of PGA is close to room temperature, ranging from 35 to 40 °C [7]. The crystallization temperature (Tc) of PGA is approximately 150 to 190 °C.

 

Products  Specification

 

Product name PGA/POLYGLYCOLIDE
CAS NO 26124-68-5
ITEM NO M265
Appearance White / milky white pellets, no impurities
Intrinsic Viscosity 0.2-2.0 dL/g
Tg 35–40 ℃
Residual Monomer <1%
Residual Solvent <0.05%
Heavy Metals <10 ppm
Density 1.3 g/cm³
Tin (Catalyst) <200 ppm
Sulfated Ash <0.05%
Melting point 220–240 ℃
Package 100g/1kg/10kg etc.
Delivery 5-8days
Storage - 20℃
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Products Application

 

PGA (CAS 26124-68-5) is mainly used in medical sutures, drug-controlled-release carriers, fracture fixation materials, and tissue engineering scaffolds, etc.

 

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FAQ

 

Q1:What is the degradation difference among PGA, PDO and PLA? 
Re: PGA degrades fastest and absorbs within 2–3 months; PDO degrades in 6–8 months; PLA has the slowest degradation of 12–24 months.

 

Q2:What are the applications of low and high IV PGA? 
Re:Low IV grade is for drug microspheres and carriers; high IV grade is for spinning sutures and injection-molded bone implants requiring good mechanical strength.

 

Q3:Could moisture-exposed PGA still be used for implant-grade products? 
Re: No. It hydrolyzes rapidly upon moisture contact, leading to molecular weight and strength loss. Implant-grade PGA requires moisture-proof frozen storage.

 

Q4: What are the degradation products of PGA and is it safe? 
Re: It degrades into glycolic acid, which can be metabolized and excreted by human body, complying with biocompatibility requirements for medical implants.

 

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