Products Description
THPP (CAS 4706-17-6) is a reducing agent, widely used for the reduction and cleavage of small molecule disulfide bonds in water-based - organic media. It can be applied in many biological experiments, such as protein cleavage and/or precipitation in molecular diagnostics, as well as in gene chips and microarrays. In addition, THPP can also be used in fields such as oil extraction, cosmetics, and electrochemical energy.
THPP is a water-soluble, odorless organic phosphorus reductant. It is more resistant to air oxidation than DTT and can achieve irreversible reduction of disulfide bonds. It is effective within a wide pH range and is suitable for IMAC/Ni-NTA purification. It can also be used in organic synthesis and compound preparation.
Products Specification
| Product name | THP/THPP/Tris(hydroxypropyl)phosphine |
| CAS NO | 4706-17-6 |
| ITEM NO | M417 |
| Appearance | 90% |
| Purity | Colorless and transparent liquid |
| pH | 1.5-12 |
| Density | 1.136 g/mL at 25 °C |
| Flash point | >110℃ |
| Package | 50mg/100mg/1g etc. |
| Delivery | 5-8days |
| Storage | room temperature |
| MSDS/COA/TDS | Connect us |
Products Application
THPP(CAS 4706-17-6) widely used in protein biochemistry and peptide synthesis, also applied as phosphine ligand for organic catalysis and metal coordination chemistry.
Apart from the core biological field, THPP has achieved large-scale applications in various fields such as oil extraction, cosmetics, nanomaterials and electrochemical energy due to its high stability and wide adaptability.
FAQ
Q1:What is the difference between THP, DTT and TCEP?
Re: THP is odorless, more oxidation-resistant with stronger reducing power than TCEP. It is compatible with Ni-NTA purification and delivers irreversible reduction.
Q2:Any storage requirement?
Re:Sensitive to oxygen. Store under inert atmosphere, cool and away from light, avoid long exposure to air.
Q3:What are the advantages of THP over TCEP?
Re: THP provides irreversible reduction, better oxidation resistance and no odor, compatible with Ni-NTA protein purification.
Q4: How stable is THP aqueous solution?
Re: Its aqueous solution is prone to oxidation by oxygen. Prepare before use, store cold and air-free for long-term storage.
Q5: What pH range is suitable for THP?
Re:It works across a wide pH range and can reduce disulfide bonds under weak acid, neutral and weak alkaline conditions.
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